Tuesday 29 November 2016
The Uncanny Valley - Cognitive Dissonance and Meta-Communication
Uncanny: Strange or mysterious, especially in an unsettling way
The uncanny is a Freudian concept of an instance where something can be familiar yet foreign at the same time, resulting in a feeling of it being uncomfortably strange.
Because the uncanny is familiar yet strange, it often creates
cognitive dissonance within the experiencing subject due to the paradoxical nature of being attracted to, yet repulsed by an object at the same time.
Just to be clear, cognitive dissonance is a condition of conflict or anxiety resulting from inconsistency between one's beliefs and one's experience/actions - such as opposing the slaughter of animals and eating meat.
Words closest to uncanny are eerie, spooky and creepy.
The concept of the uncanny valley was put forward by Masahiro Mori in 1970 (see also Energy, Vol 7(4), 33-35, 1970). Professor Mori was designing robots that were becoming more humanlike in appearance. It is interesting to follow his reasoning about how the appearance of a robot influences the feeling of familiarity/empathy or otherwise in people.
On one extreme are the industrial robots who do not have any specific shape and structure. They are designed to do a particular job - like welding car parts - and their presence hardly generate a reaction in us. The familiarity is zero.
The next stage is humanoid robots with shape like a human body with two hands, feet, eyes etc. but it is difficult to confuse them with a real human (ASIMO is a good example). They generate a feeling of curiosity and affection and are much more noticeable than an industrial robot. The familiarity is positive - we do not feel strange in their presence. The familiarity increases further as robots become more humanlike but are different enough not to be confused with real persons.
However, a point is reached when the robot might look like a human but have attributes that are definitely not humanlike. For example, a robot's hand will feel hard and cold - nothing like the hand of a real human. A prosthetic hand creates a feeling of strangeness or negative familiarity. Your mind is telling you that the robot is a human but then there are things about it that are not normal - this creates cognitive dissonance.
Now, consider a robot that can imitate human facial expressions. Given a large enough number of muscles, the distortion and speed of the facial muscles and eye movement may be controlled to reproduce natural expressions of a human face. Such a robot will generate a lot of empathy as you are willing to accept that it might be like you.
However, if the speed and/or movement of its facial and eye muscles is not synchronized, the robot will seem rather strange and we shall start to get an eerie feeling - negative familiarity. It is a situation akin to somebody having a twitch in facial muscles and the feeling of unease it generates in others - the empathy changes to unease - interestingly, only a small change is all that is needed.
Another example is that of a corpse - humanlike in appearance but motionless and cold; and again generates a strange feeling of unease in people.
Essentially, familiarity increases as an inanimate object starts to acquire more human like attributes until it is almost humanlike when the familiarity takes a dip, but rises again when the object is very much like a human in both form and behaviour. This may be particularly so if we look at the robot from a distance when the small differences from a real human are not as noticeable. The dip in familiarity can be sudden - Professor Mori called the dip the uncanny valley and expressed the situation as a hypothetical graph that is shown below.
The response is enhanced by movement. A prosthetic hand feels strange to touch and hold. But a moving prosthetic will definitely generate a stronger response. Think of a dead body that for some reason shows sudden movement - this will generate a feeling of horror and revulsion. The uncanny valley has rather steep sides. The uncanny works both ways.
The uncanny valley can also be created by photoshopped images, by people who have undergone unsuccessful plastic surgery or by discrepancies in voice and movement. Many movies incorporating animations failed at the box-office because the characters were depicted as humans but failed to display proper holistic human characteristics.
Is Uncanny Valley Real? Many people have questioned if uncanny valley indeed exists or is it simply a hypothesis that sounds interesting but without substance? To my mind uncanny valley does make sense as it resonates with my personal experience. Mathur and Reichling have done a detailed scientific study and find convincing support for its existence. I show their results in the following two sides:
Monkeys sense uncanny valley too: An interesting study with macaque monkeys was performed in Princeton University. Monkeys are a social group and normally coo and smack their lips to engage each other. In the experiment, when monkeys were shown the close-to-real images, they quickly avert their glances and appear frightened. However, when asked to peer at the less-close-to-real faces or real faces, they viewed them more often and for longer periods.
Why does the uncanny valley exist?
It really boils down to how humans communicate. All information include meta-communication - have cues about how a piece of information is meant to be interpreted - the same message accompanied by different meta-communication can mean something entirely different.
Much of human communication is non-verbal - body language like facial expression, posture, hand movements play a big part too. In relation to verbal communication (spoken words), the paralinguistic properties (pitch, volume, intonations etc.) play an important role in human communications. Absence of meta-communication in speech disrupts the ability of the listener to interpret its full meaning appropriately; leaving a gap in communication from somebody who otherwise is expected to have this ability. The uncanny valley effect is a manifestation of the hostility towards those who do not possess proper paralinguistic ability.
Cultural and social norms play an important role in meta-communications too. These may accentuate the uncanny valley effect further.
The uncanny effect points us to understand how we can design robots that are more acceptable to a large section of the population. Humanoid robots are here to stay - we encounter them frequently in movies and creative industry. How they are depicted has been key to the success of particular offerings - the uncanny valley effect can explain the failure of many of these enterprises. Better understanding of what causes the uncanny valley and how to avoid it is important for the progress in robotics and other fields.
Monday 21 November 2016
Megatrends Driven by Exponentially Growing Technologies
Blog Content - Who am I?
(Click on a slide to view in full size - press escape to return to text)
Megatrends are large, transformative global forces that impact everyone on the planet. EY Megatrends Report 2015
Some examples of megatrends: To introduce the subject, I start by mentioning three megatrends that are not technology driven but are well established. Megatrends are like supertankers whose direction is very difficult to alter - once established they evolve with time and their consequences require co-operative efforts from all nations of the world.
1. Demographic Shifts: It is projected that global population will increase by more than 1.5 billion by 2050. There are three trends in this shift:
a. Population increase will be highest in African and Middle Eastern countries who will be responsible for 50% of global population increase. Japan and Russia might actually see a decline of about 15%.
b. 65 years or older will triple from 500 million in 2010 to 1500 million in 2050.
c. Spending power of the global middle class will increase from US$21 trillion in 2010 to $56 trillion in 2030. Middle Class in Asia-Pacific countries will increase their share from 24% to 56%.
2. Shift to Cities: Global urban population will increase from 3.8 billion in 2010 to 4.9 billion in 2030 and 6.5 billion by 2050. 1.5 million people are added to global urban population every week.
3. Climate Change: Climate change will impact on agriculture and food resources, demand for which is expected to increase by 40 percents by 2030. Extreme weather will devastate many areas and rising sea levels will also seriously affect big cities near coastlines. Center for Global Development has an interactive website for mapping the impacts of climate change that is worth a visit and some mouse-work.
Megatrends happen as a result of complex interplay between social, industrial, economic and technological developments. This blog concerns with megatrends engendered and supported by growth in technology and analyses how these impact our social, industrial and personal development.
Not a day goes by when I do not come across the phrase - Technology is growing exponentially. To my mind, exponential growth eventually brings an unimaginable rate of change. Humans perceive the world in a linear fashion where things around them change in an incremental fashion and extrapolation over a period - days or even decades - may be easily perceived. This is how humans have lived since the beginning - the past 100 years excepted when consequences of exponential growth have been felt.
A good illustration of exponential growth is to work out how population of a bacterial colony increases with time. A single bacterium that doubles in number every minute will grow to a population of more than a trillion trillion after one hour - half of these will be produced in the final minute!
For a fascinating account of exponential growth - click here
Technology is now growing exponentially - the doubling rate of many capabilities follows the so called Moor's Law and is measured in a small number of years. A technological capability that doubles every year will be a trillion trillion times more advanced in 60 years. In the following, I show some trends in technologies in three area over the past half century:
The increased technological capability feeds itself into our society in many ways - industrially, it becomes more efficient and cheaper to produce goods, a far greater variety of products are possible, social norms, medical care, transport, forensics, leisure will all be impacted. At the same time cybercrime, loss of privacy, psychiatric problems will be expected to impact the society in a negative way. It might be interesting to project how life might change in the coming decades. This might be a dodgy exercise as the exponential changes in technologies can create unknown unknowns that are things that we do not even know are possible but suddenly appear to have a major influence. Exponentially increasing technology has already reached a stage that, in many areas, it can improve itself without external human input - this creates a higher growth rate - called the accelerating growth - characterized by much reduced doubling times. A consequence of this is that changes that we expect to happen in say 20 years time might happen in 5 years or even much sooner. Forecasting future becomes very difficult then.
Historical Perspective: Past sixty years or so have been critical in terms of the transition from macro- to nano- technologies.
This transition has gone hand in hand with the understanding of how matter behaves at the atomic and molecular level. In biological sciences, the understanding of the structure of DNA was the tipping point while in digital technology discovery of the semiconductor transistor triggered the process of device miniaturization. The following two slides, borrowed from my lecture series on nanotechnology, demonstrate how such transitions have happened:
The three technologies - nanotech (NT), biotech/genetics (GT) and digital/cyber (DT) - will have profound impact on our future and will determine megatrends that is the subject of this blog. NT gives us the capability of handling and manipulating matter at atomic and molecular level while DT allows analysis, transfer and storage of large body of data. Active structures of devices in the two technologies operate at the scale of a few nanometers and have gained from a kind of beneficial symbiosis that has enabled their rapid development. DT is largely software-enabled; Micro-electronics and NT provide capability to miniaturize hardware devices. In not too distant future, the world and what people can do will be increasingly driven by software-enabled devices that will progressively become even smaller. The scale and speed of the changes driven by exponentially growing technologies will be difficult to absorb by our society.
Biotech/genetics (GT) operates on truly molecular level and derives great benefits from the miniaturization of devices (NT) and superior analytical capabilities afforded by DT.
In the following, I discuss some of the megatrends driven by the three technologies
Digital Technology: DT has already made a big impact on the society. World Economic Forum (WEF) has looked at megatrends of DT in their 2015 report - this is accompanied by an extensive document.
Let me briefly expand on these megatrends: Access to the internet is the primary means to communicate and share information. More and more people are using mobile devices to connect to the internet and this trend should continue. As devices become smaller, they will be implanted in bodies and serve a host of functions - communication, location and behaviour monitoring, health functions like measuring and sending health related parameters to health centers and automatically releasing healing medicines. In more distant future, implanted devices will be able to communicate unexpressed thoughts or moods by reading brainwaves and other signals.
Connecting inanimate objects to the internet is a growing trend commonly known as the Internet of Things (IoT). Essentially, many objects in buildings will be connected to the internet - they can exchange their status and be controllable remotely. For example, the refrigerator in the house can keep track of what is in it and can order items automatically. Or light bulbs may be switched on and off remotely using Wifi. Homes and offices will become smart. There is a certain unease about IoT in terms of security. Legislation is not in place and most companies manufacturing connectable devices have not paid sufficient attention to cyber-security. In due course it is hoped that this problem will be solved and IoT will become ubiquitous.
Digitization of Matter (3D printing and creating of physical materials based on digitally transmitted parameters)
3D printing allows products to be printed locally and on demand. Products can be made to personal specifications; e.g. particular shaped foot requires a specialized shoe size. Bottom-up fabrication will reduce energy costs and waste, will make goods cheaper and generate a lot of creative activity.
The major negative impact of 3D printing will be felt in patent infringements, piracy and product quality. It will be difficult to control production of offensive weapons etc.
Bio-Printing: An organ may be printed layer by layer and can be customized in shape, size and even genetically to match the particular requirement. This will be a game changer in terms of human medical care. For example, the crown for a tooth can be 3D printed to fit exactly or prosthetic body parts.
The negative aspects of bio-printing are to do with ethical concerns. Also, if any body part may be printed and replaced then there will be little incentive to look after your health. 3D printing will have a serious impact on the way the society operates.
Artificial Intelligence (AI) and Robotics: The trend here is of computers becoming more intelligent. The situation now is that computers are capable of performing some tasks at a superhuman level while being hopeless in solving anything else. This is artificial narrow intelligence (ANI) - we already have robots (which are really just intelligent computers) that perform a host of mostly industrially useful functions. With exponentially increasing technology, computers can achieve artificial general intelligence (AGI) and be as intelligent as humans in a reasonably large number of areas. AGI will then start to replace humans in many jobs - particularly in services and administrative support. It is possible that in the next 10-20 years half of the jobs as we have them today will be performed by intelligent machines (robots). This will create unemployment although alternate jobs will appear in leisure and recreational industries.
TRANSPORT: Currently, our transport system is heavily reliant on fossil fuel - this has resulted in increased emission of green house gases (GHG) allegedly responsible for climate change. A shift from fossil fuel to electric vehicles (EV) is being talked about and in the next 30-40 years most cars on the road might be EVs. An additional change is that with increasing analytical capabilities of computers and sensors, driverless cars (autonomous vehicles - AV) are also being tested with promising results. These developments depend largely on our ability to store energy - battery technology - and a range of about 200 miles for EVs is achievable. The megatrend firmly points to the replacement of fossil fuel powered vehicles to EVs and then to AVs.
Megatrends in Medicine:
"Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less, in human beings of whom they know nothing" ...Voltaire (1694-1778)
The situation has changed dramatically in the past 50 years - it will be fair to say that we now have a good understanding of the molecular basis of living systems and the causes of disease. The most important development in medicine in recent years has been the understanding of the human genome. Technology now allows mapping 30,000 genes of a human genome for about $1000. This has opened up the possibility of genomics medicine - the doctor instead of detecting and treating a disease can now focus on predicting and preventing it.
Based on individual genomic information, the doctor can select a medicine that is active and safe for that person - the specificity will deliver the maximum efficacy in the treatment with minimal side effects.
Many diseases like sickle cell anemia are caused by a defective gene. In gene therapy, a new gene is introduced in the genome to replace the defective gene and cure the disease. Gene therapy will be increasingly used in the future. The newly discovered gene editing technique CRISPR is easier, faster and cheaper than previous methods of modifying DNA at precise locations. CRISPR will allow permanent modification of genes in living cells and treat genetic causes of disease.
CRISPR has implications for everything - from treating cancer and other diseases, eradicating genetic malfunctions that cause disease, to increasing crop yields or creating efficient biofuels. We shall see growing application of CRISPR in the next decade.
Molecular Imaging and Nuclear Medicine: Until recently, medical diagnostic imaging methods - X-rays, ultrasound and computer aided tomography (CT) - had offered high resolution images of anatomical structures and have been valuable tools. Molecular imaging provides detailed information of what is happening inside the human body at the molecular and cellular level - it actually tells us how the body is functioning and measures chemical and biological changes happening in real time.
For an outreach course on medical imaging click here.
Molecular imaging offers unique insights inside of the human body without the need of biopsy or surgery. It can locate disease like cancers in the earliest stages, often before symptoms occur.
Molecular imaging includes the field of nuclear medicine which uses very small amounts of radioactive isotopes - radiopharmaceuticals - to diagnose and treat disease.
Nanotechnology in medicine: Nanotechnology (NT)
For an outreach course on nanotechnology click here
For an outreach talk on nano-medicine click here
Nanotechnology is already making serious impact in medicine. This is because biological systems and their disease work at molecular level. These were inaccessible in the past but with nanotechnology, we can now probe and modify them at the molecular level and directly address the problem of diagnosis, detection, drug delivery etc. The current progress is already very impressive:
Megatrends in Nanotechnology: A nano or nano-meter is one billionth of a meter. NT is the study, design, synthesis, manipulation and application of materials and devices at nano scale. NT will create devices with unique properties - devices will be faster, lighter, stronger, more efficient and cheaper. Materials at nano scale show entirely new phenomenon and properties - nano-particles (NP) have very large surface area and can be millions of time more reactive than macro scale matter. Additionally, matter at nano scale is largely governed by the laws of quantum physics and behaves very differently from ordinary matter.
I have described how NT is already having a serious impact on medicine and to some extent on digital technology by reducing device size. In a more general context, NT will affect all aspects of our life. Nanoparticles are excellent catalysts, superb lubricants, are used in self-cleaning window glass, suntan lotions, bullet-proof vest, and many other industrial applications - too numerous to list. See also. NT will make bottom-up manufacturing feasible and reduce waste enormously.
Miniaturization is driven by NT - we can have nanometer size machines, computer memory chips, sensors of all types. The megatrend of NT making inroads into the way manufacturing, medical care, communications are performed is firmly established.
FINAL WORD: Megatrends I have discussed here are not predictions or fiction. These are trends that are firmly established and will happen over the next few decades. What is not certain and difficult to say is the way the accelerating growth in technology might impact these trends - by making them happen quicker or springing surprises that can make these megatrends obsolete even before they have run theri course. One thing is for certain - future will be interesting and our civilization will not be prepared for the changes to come.
(Click on a slide to view in full size - press escape to return to text)
Megatrends are large, transformative global forces that impact everyone on the planet. EY Megatrends Report 2015
Some examples of megatrends: To introduce the subject, I start by mentioning three megatrends that are not technology driven but are well established. Megatrends are like supertankers whose direction is very difficult to alter - once established they evolve with time and their consequences require co-operative efforts from all nations of the world.
1. Demographic Shifts: It is projected that global population will increase by more than 1.5 billion by 2050. There are three trends in this shift:
a. Population increase will be highest in African and Middle Eastern countries who will be responsible for 50% of global population increase. Japan and Russia might actually see a decline of about 15%.
b. 65 years or older will triple from 500 million in 2010 to 1500 million in 2050.
c. Spending power of the global middle class will increase from US$21 trillion in 2010 to $56 trillion in 2030. Middle Class in Asia-Pacific countries will increase their share from 24% to 56%.
2. Shift to Cities: Global urban population will increase from 3.8 billion in 2010 to 4.9 billion in 2030 and 6.5 billion by 2050. 1.5 million people are added to global urban population every week.
3. Climate Change: Climate change will impact on agriculture and food resources, demand for which is expected to increase by 40 percents by 2030. Extreme weather will devastate many areas and rising sea levels will also seriously affect big cities near coastlines. Center for Global Development has an interactive website for mapping the impacts of climate change that is worth a visit and some mouse-work.
Megatrends happen as a result of complex interplay between social, industrial, economic and technological developments. This blog concerns with megatrends engendered and supported by growth in technology and analyses how these impact our social, industrial and personal development.
Not a day goes by when I do not come across the phrase - Technology is growing exponentially. To my mind, exponential growth eventually brings an unimaginable rate of change. Humans perceive the world in a linear fashion where things around them change in an incremental fashion and extrapolation over a period - days or even decades - may be easily perceived. This is how humans have lived since the beginning - the past 100 years excepted when consequences of exponential growth have been felt.
A good illustration of exponential growth is to work out how population of a bacterial colony increases with time. A single bacterium that doubles in number every minute will grow to a population of more than a trillion trillion after one hour - half of these will be produced in the final minute!
For a fascinating account of exponential growth - click here
Technology is now growing exponentially - the doubling rate of many capabilities follows the so called Moor's Law and is measured in a small number of years. A technological capability that doubles every year will be a trillion trillion times more advanced in 60 years. In the following, I show some trends in technologies in three area over the past half century:
Historical Perspective: Past sixty years or so have been critical in terms of the transition from macro- to nano- technologies.
This transition has gone hand in hand with the understanding of how matter behaves at the atomic and molecular level. In biological sciences, the understanding of the structure of DNA was the tipping point while in digital technology discovery of the semiconductor transistor triggered the process of device miniaturization. The following two slides, borrowed from my lecture series on nanotechnology, demonstrate how such transitions have happened:
The three technologies - nanotech (NT), biotech/genetics (GT) and digital/cyber (DT) - will have profound impact on our future and will determine megatrends that is the subject of this blog. NT gives us the capability of handling and manipulating matter at atomic and molecular level while DT allows analysis, transfer and storage of large body of data. Active structures of devices in the two technologies operate at the scale of a few nanometers and have gained from a kind of beneficial symbiosis that has enabled their rapid development. DT is largely software-enabled; Micro-electronics and NT provide capability to miniaturize hardware devices. In not too distant future, the world and what people can do will be increasingly driven by software-enabled devices that will progressively become even smaller. The scale and speed of the changes driven by exponentially growing technologies will be difficult to absorb by our society.
Biotech/genetics (GT) operates on truly molecular level and derives great benefits from the miniaturization of devices (NT) and superior analytical capabilities afforded by DT.
In the following, I discuss some of the megatrends driven by the three technologies
Digital Technology: DT has already made a big impact on the society. World Economic Forum (WEF) has looked at megatrends of DT in their 2015 report - this is accompanied by an extensive document.
Let me briefly expand on these megatrends: Access to the internet is the primary means to communicate and share information. More and more people are using mobile devices to connect to the internet and this trend should continue. As devices become smaller, they will be implanted in bodies and serve a host of functions - communication, location and behaviour monitoring, health functions like measuring and sending health related parameters to health centers and automatically releasing healing medicines. In more distant future, implanted devices will be able to communicate unexpressed thoughts or moods by reading brainwaves and other signals.
Connecting inanimate objects to the internet is a growing trend commonly known as the Internet of Things (IoT). Essentially, many objects in buildings will be connected to the internet - they can exchange their status and be controllable remotely. For example, the refrigerator in the house can keep track of what is in it and can order items automatically. Or light bulbs may be switched on and off remotely using Wifi. Homes and offices will become smart. There is a certain unease about IoT in terms of security. Legislation is not in place and most companies manufacturing connectable devices have not paid sufficient attention to cyber-security. In due course it is hoped that this problem will be solved and IoT will become ubiquitous.
Digitization of Matter (3D printing and creating of physical materials based on digitally transmitted parameters)
3D printing allows products to be printed locally and on demand. Products can be made to personal specifications; e.g. particular shaped foot requires a specialized shoe size. Bottom-up fabrication will reduce energy costs and waste, will make goods cheaper and generate a lot of creative activity.
The major negative impact of 3D printing will be felt in patent infringements, piracy and product quality. It will be difficult to control production of offensive weapons etc.
Bio-Printing: An organ may be printed layer by layer and can be customized in shape, size and even genetically to match the particular requirement. This will be a game changer in terms of human medical care. For example, the crown for a tooth can be 3D printed to fit exactly or prosthetic body parts.
The negative aspects of bio-printing are to do with ethical concerns. Also, if any body part may be printed and replaced then there will be little incentive to look after your health. 3D printing will have a serious impact on the way the society operates.
Artificial Intelligence (AI) and Robotics: The trend here is of computers becoming more intelligent. The situation now is that computers are capable of performing some tasks at a superhuman level while being hopeless in solving anything else. This is artificial narrow intelligence (ANI) - we already have robots (which are really just intelligent computers) that perform a host of mostly industrially useful functions. With exponentially increasing technology, computers can achieve artificial general intelligence (AGI) and be as intelligent as humans in a reasonably large number of areas. AGI will then start to replace humans in many jobs - particularly in services and administrative support. It is possible that in the next 10-20 years half of the jobs as we have them today will be performed by intelligent machines (robots). This will create unemployment although alternate jobs will appear in leisure and recreational industries.
TRANSPORT: Currently, our transport system is heavily reliant on fossil fuel - this has resulted in increased emission of green house gases (GHG) allegedly responsible for climate change. A shift from fossil fuel to electric vehicles (EV) is being talked about and in the next 30-40 years most cars on the road might be EVs. An additional change is that with increasing analytical capabilities of computers and sensors, driverless cars (autonomous vehicles - AV) are also being tested with promising results. These developments depend largely on our ability to store energy - battery technology - and a range of about 200 miles for EVs is achievable. The megatrend firmly points to the replacement of fossil fuel powered vehicles to EVs and then to AVs.
Megatrends in Medicine:
"Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less, in human beings of whom they know nothing" ...Voltaire (1694-1778)
The situation has changed dramatically in the past 50 years - it will be fair to say that we now have a good understanding of the molecular basis of living systems and the causes of disease. The most important development in medicine in recent years has been the understanding of the human genome. Technology now allows mapping 30,000 genes of a human genome for about $1000. This has opened up the possibility of genomics medicine - the doctor instead of detecting and treating a disease can now focus on predicting and preventing it.
Based on individual genomic information, the doctor can select a medicine that is active and safe for that person - the specificity will deliver the maximum efficacy in the treatment with minimal side effects.
Many diseases like sickle cell anemia are caused by a defective gene. In gene therapy, a new gene is introduced in the genome to replace the defective gene and cure the disease. Gene therapy will be increasingly used in the future. The newly discovered gene editing technique CRISPR is easier, faster and cheaper than previous methods of modifying DNA at precise locations. CRISPR will allow permanent modification of genes in living cells and treat genetic causes of disease.
CRISPR has implications for everything - from treating cancer and other diseases, eradicating genetic malfunctions that cause disease, to increasing crop yields or creating efficient biofuels. We shall see growing application of CRISPR in the next decade.
Molecular Imaging and Nuclear Medicine: Until recently, medical diagnostic imaging methods - X-rays, ultrasound and computer aided tomography (CT) - had offered high resolution images of anatomical structures and have been valuable tools. Molecular imaging provides detailed information of what is happening inside the human body at the molecular and cellular level - it actually tells us how the body is functioning and measures chemical and biological changes happening in real time.
For an outreach course on medical imaging click here.
Molecular imaging offers unique insights inside of the human body without the need of biopsy or surgery. It can locate disease like cancers in the earliest stages, often before symptoms occur.
Molecular imaging includes the field of nuclear medicine which uses very small amounts of radioactive isotopes - radiopharmaceuticals - to diagnose and treat disease.
Nanotechnology in medicine: Nanotechnology (NT)
For an outreach course on nanotechnology click here
For an outreach talk on nano-medicine click here
Nanotechnology is already making serious impact in medicine. This is because biological systems and their disease work at molecular level. These were inaccessible in the past but with nanotechnology, we can now probe and modify them at the molecular level and directly address the problem of diagnosis, detection, drug delivery etc. The current progress is already very impressive:
Megatrends in Nanotechnology: A nano or nano-meter is one billionth of a meter. NT is the study, design, synthesis, manipulation and application of materials and devices at nano scale. NT will create devices with unique properties - devices will be faster, lighter, stronger, more efficient and cheaper. Materials at nano scale show entirely new phenomenon and properties - nano-particles (NP) have very large surface area and can be millions of time more reactive than macro scale matter. Additionally, matter at nano scale is largely governed by the laws of quantum physics and behaves very differently from ordinary matter.
I have described how NT is already having a serious impact on medicine and to some extent on digital technology by reducing device size. In a more general context, NT will affect all aspects of our life. Nanoparticles are excellent catalysts, superb lubricants, are used in self-cleaning window glass, suntan lotions, bullet-proof vest, and many other industrial applications - too numerous to list. See also. NT will make bottom-up manufacturing feasible and reduce waste enormously.
Miniaturization is driven by NT - we can have nanometer size machines, computer memory chips, sensors of all types. The megatrend of NT making inroads into the way manufacturing, medical care, communications are performed is firmly established.
FINAL WORD: Megatrends I have discussed here are not predictions or fiction. These are trends that are firmly established and will happen over the next few decades. What is not certain and difficult to say is the way the accelerating growth in technology might impact these trends - by making them happen quicker or springing surprises that can make these megatrends obsolete even before they have run theri course. One thing is for certain - future will be interesting and our civilization will not be prepared for the changes to come.
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